Hydro, azo, azoxy
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چکیده
منابع مشابه
Anti-androgenic activity of substituted azo- and azoxy-benzene derivatives.
Substituted phenylazo and phenylazoxy compounds were systematically prepared and their anti-androgenic activity was measured in terms of (1) the growth-inhibiting effect on an androgen-dependent cell line, SC-3, and (2) the binding affinity to nuclear androgen receptor. Generally, azo/azoxy compounds showed cell toxicity, and the growth-inhibiting effects on SC-3 cells correlated with the toxic...
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Procarbazine, a chemotherapeutic hydrazine, is thought to be metabolized to an alkylating species similar to methyl carbonium ion by multistep reactions involving cytochrome P-450, monoamine oxidase, and cytosolic enzymes. The DNA-damaging and cytotoxic potential of procarbazine and its metabolites in murine L1210 leukemia tumor cells in vitro was determined using alkaline elution techniques an...
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Series of elongated azo esters containing three rings with methyl moiety as one of the terminal carbon chain and various substituents R(R=H,CH3,OCH3,NO2,Cl) at the other end of the molecule have been isolated , and their structure were were characterized by H-NMR and IR as well as elemental analysis . The mesomorphic properties of these compounds were investigated via differential scanning calo...
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ژورنال
عنوان ژورنال: Nature
سال: 1976
ISSN: 0028-0836,1476-4687
DOI: 10.1038/259162c0